Cart
sales@molnova.com
Home - Products - Antibody Drug Conjugates (ADC) - ADC Cytotoxin - MMAD hydrochloride

MMAD hydrochloride

CAS No. 173441-26-4

MMAD hydrochloride ( Demethyldolastatin 10 hydrochloride;Monomethylauristatin D hydrochloride )

Catalog No. M12633 CAS No. 173441-26-4

A potent tubulin inhibitor that is a toxin payload in antibody drug conjugates (ADCs).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    MMAD hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent tubulin inhibitor that is a toxin payload in antibody drug conjugates (ADCs).
  • Description
    A potent tubulin inhibitor that is a toxin payload in antibody drug conjugates (ADCs).
  • Synonyms
    Demethyldolastatin 10 hydrochloride;Monomethylauristatin D hydrochloride
  • Pathway
    Antibody Drug Conjugates (ADC)
  • Target
    ADC Cytotoxin
  • Recptor
    ADC Cytotoxin
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    173441-26-4
  • Formula Weight
    807.53
  • Molecular Formula
    C41H67ClN6O6S
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    ——
  • Chemical Name
    L-Valinamide, N-methyl-L-valyl-N-[(1S,2R)-2-methoxy-4-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(2-thiazolyl)ethyl]amino]propyl]-1-pyrrolidinyl]-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-, hydrochloride (1:1)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Chudasama V, et al. Nat Chem. 2016 Feb;8(2):114-9.
2. Leal M, et al. Bioconjug Chem. 2015 Nov 18;26(11):2223-32.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Daunorubicin hydroch...

    Daunorubicin is potent topoisomerase II (Topo II) inhibitor, interacts with DNA by intercalation and inhibition of macromolecular biosynthesis in cancer cells.

  • Mertansine

    Mertansine (DM1) is a tubulin inhibitor; thiol-containing maytansinoid that create an antibody-drug conjugate (ADC); an ADC payload.

  • PNU-159682

    A highly potent metabolite of the anthracycline nemorubicin with outstanding cytotoxicity; a topoisomerase inhibitor and ADCs cytotoxin.

Sign In Join Free